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Zhibo Yang

TitleAssociate Professor
InstitutionUniversity of Oklahoma, Norman
DepartmentChemistry/Biochemistry
Address620 Parrington Oval
Norman OK 73019
Phone405/325-1772
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    R01GM116116     (YANG, ZHIBO)Aug 1, 2015 - Jul 31, 2021
    NIH
    From Single Cells to Tissues: a Novel Mass Spectrometry Approach for Bioanalysis
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ahsan N, Rao RSP, Wilson RS, Punyamurtula U, Salvato F, Petersen M, Ahmed MK, Abid MR, Verburgt JC, Kihara D, Yang Z, Fornelli L, Foster SB, Ramratnam B. Mass spectrometry-based proteomic platforms for better understanding of SARS-CoV-2 induced pathogenesis and potential diagnostic approaches. Proteomics. 2021 Apr 16; e2000279. PMID: 33860983.
      Citations:    
    2. Yang J, Pei Z, Deng J, Mao Y, Wu Q, Yang Z, Wang B, Aikens CM, Liang W, Shao Y. Correction: Analysis and visualization of energy densities. I. Insights from real-time time-dependent density functional theory simulations. Phys Chem Chem Phys. 2021 Apr 14; 23(14):8936. PMID: 33876053.
      Citations:    
    3. Bensen RC, Standke SJ, Colby DH, Kothapalli NR, Le-McClain AT, Patten MA, Tripathi A, Heinlen JE, Yang Z, Burgett AWG. Single Cell Mass Spectrometry Quantification of Anticancer Drugs: Proof of Concept in Cancer Patients. ACS Pharmacol Transl Sci. 2021 Feb 12; 4(1):96-100. PMID: 33615163.
      Citations:    
    4. Yang J, Pei Z, Deng J, Mao Y, Wu Q, Yang Z, Wang B, Aikens CM, Liang W, Shao Y. Analysis and visualization of energy densities. I. Insights from real-time time-dependent density functional theory simulations. Phys Chem Chem Phys. 2020 Dec 07; 22(46):26838-26851. PMID: 33170198.
      Citations:    Fields:    
    5. Liu R, Yang Z. Single cell metabolomics using mass spectrometry: Techniques and data analysis. Anal Chim Acta. 2021 Jan 25; 1143:124-134. PMID: 33384110.
      Citations: 1     Fields:    
    6. Zhu Y, Wang W, Yang Z. Combining Mass Spectrometry with Paternò-Büchi Reaction to Determine Double-Bond Positions in Lipids at the Single-Cell Level. Anal Chem. 2020 08 18; 92(16):11380-11387. PMID: 32678580.
      Citations: 2     Fields:    
    7. Pan N, Rao W, Yang Z. Single-Probe Mass Spectrometry Analysis of Metabolites in Single Cells. Methods Mol Biol. 2020; 2064:61-71. PMID: 31565766.
      Citations:    Fields:    Translation:HumansCells
    8. Tao Y, Pei Z, Bellonzi N, Mao Y, Zou Z, Liang W, Yang Z, Shao Y. Constructing Spin-Adiabatic States for the Modeling of Spin-Crossing Reactions. I. A Shared-Orbital Implementation. Int J Quantum Chem. 2020 Mar 15; 120(6). PMID: 32773885.
      Citations:    
    9. Liu M, Zhang Y, Yang J, Cui X, Zhou Z, Zhan H, Ding K, Tian X, Yang Z, Fung KA, Edil BH, Postier RG, Bronze MS, Fernandez-Zapico ME, Stemmler MP, Brabletz T, Li YP, Houchen CW, Li M. ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin a3ß1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells. Gastroenterology. 2020 02; 158(3):679-692.e1. PMID: 31711924.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    10. Tian X, Xie B, Zou Z, Jiao Y, Lin LE, Chen CL, Hsu CC, Peng J, Yang Z. Multimodal Imaging of Amyloid Plaques: Fusion of the Single-Probe Mass Spectrometry Image and Fluorescence Microscopy Image. Anal Chem. 2019 10 15; 91(20):12882-12889. PMID: 31536324.
      Citations:    Fields:    Translation:Animals
    11. Liu R, Sun M, Zhang G, Lan Y, Yang Z. Towards early monitoring of chemotherapy-induced drug resistance based on single cell metabolomics: Combining single-probe mass spectrometry with machine learning. Anal Chim Acta. 2019 Dec 27; 1092:42-48. PMID: 31708031.
      Citations: 1     Fields:    Translation:HumansCells
    12. Zhu Y, Liu R, Yang Z. Redesigning the T-probe for mass spectrometry analysis of online lysis of non-adherent single cells. Anal Chim Acta. 2019 Nov 25; 1084:53-59. PMID: 31519234.
      Citations: 4     Fields:    Translation:HumansCells
    13. Pan N, Standke SJ, Kothapalli NR, Sun M, Bensen RC, Burgett AWG, Yang Z. Quantification of Drug Molecules in Live Single Cells Using the Single-Probe Mass Spectrometry Technique. Anal Chem. 2019 07 16; 91(14):9018-9024. PMID: 31246408.
      Citations: 4     Fields:    Translation:HumansCells
    14. Standke SJ, Colby DH, Bensen RC, Burgett AWG, Yang Z. Integrated Cell Manipulation Platform Coupled with the Single-probe for Mass Spectrometry Analysis of Drugs and Metabolites in Single Suspension Cells. J Vis Exp. 2019 06 21; (148). PMID: 31282898.
      Citations:    Fields:    Translation:HumansCells
    15. Tian X, Zhang G, Zou Z, Yang Z. Anticancer Drug Affects Metabolomic Profiles in Multicellular Spheroids: Studies Using Mass Spectrometry Imaging Combined with Machine Learning. Anal Chem. 2019 05 07; 91(9):5802-5809. PMID: 30951294.
      Citations: 5     Fields:    Translation:HumansCells
    16. Liu R, Zhang G, Sun M, Pan X, Yang Z. Integrating a generalized data analysis workflow with the Single-probe mass spectrometry experiment for single cell metabolomics. Anal Chim Acta. 2019 Aug 08; 1064:71-79. PMID: 30982520.
      Citations: 4     Fields:    Translation:Humans
    17. Standke SJ, Colby DH, Bensen RC, Burgett AWG, Yang Z. Mass Spectrometry Measurement of Single Suspended Cells Using a Combined Cell Manipulation System and a Single-Probe Device. Anal Chem. 2019 02 05; 91(3):1738-1742. PMID: 30644722.
      Citations: 12     Fields:    Translation:HumansCells
    18. Roberts BL, Severance ZC, Bensen RC, Le AT, Kothapalli NR, Nuñez JI, Ma H, Wu S, Standke SJ, Yang Z, Reddig WJ, Blewett EL, Burgett AWG. Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity. ACS Chem Biol. 2019 02 15; 14(2):276-287. PMID: 30576108.
      Citations: 3     Fields:    Translation:HumansCells
    19. Liu R, Zhang G, Yang Z. Towards rapid prediction of drug-resistant cancer cell phenotypes: single cell mass spectrometry combined with machine learning. Chem Commun (Camb). 2019 Jan 10; 55(5):616-619. PMID: 30525135.
      Citations: 12     Fields:    Translation:HumansCells
    20. Sun M, Yang Z. Metabolomic Studies of Live Single Cancer Stem Cells Using Mass Spectrometry. Anal Chem. 2019 02 05; 91(3):2384-2391. PMID: 30582812.
      Citations: 13     Fields:    Translation:HumansCells
    21. Liu R, Pan N, Zhu Y, Yang Z. T-Probe: An Integrated Microscale Device for Online In Situ Single Cell Analysis and Metabolic Profiling Using Mass Spectrometry. Anal Chem. 2018 09 18; 90(18):11078-11085. PMID: 30119596.
      Citations: 14     Fields:    Translation:HumansCells
    22. Sun M, Yang Z, Wawrik B. Metabolomic Fingerprints of Individual Algal Cells Using the Single-Probe Mass Spectrometry Technique. Front Plant Sci. 2018; 9:571. PMID: 29760716.
      Citations:    
    23. Tian X, Zhang G, Shao Y, Yang Z. Towards enhanced metabolomic data analysis of mass spectrometry image: Multivariate Curve Resolution and Machine Learning. Anal Chim Acta. 2018 Dec 11; 1037:211-219. PMID: 30292295.
      Citations: 5     Fields:    Translation:Animals
    24. Du L, Risinger AL, Mitchell CA, You J, Stamps BW, Pan N, King JB, Bopassa JC, Judge SIV, Yang Z, Stevenson BS, Cichewicz RH. Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E8957-E8966. PMID: 29073092.
      Citations: 4     Fields:    Translation:AnimalsCells
    25. Sun M, Tian X, Yang Z. Microscale Mass Spectrometry Analysis of Extracellular Metabolites in Live Multicellular Tumor Spheroids. Anal Chem. 2017 09 05; 89(17):9069-9076. PMID: 28753268.
      Citations: 9     Fields:    Translation:HumansCells
    26. Pan N, Rao W, Standke SJ, Yang Z. Using Dicationic Ion-Pairing Compounds To Enhance the Single Cell Mass Spectrometry Analysis Using the Single-Probe: A Microscale Sampling and Ionization Device. Anal Chem. 2016 07 05; 88(13):6812-9. PMID: 27239862.
      Citations: 15     Fields:    Translation:HumansCells
    27. Rao W, Pan N, Yang Z. Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions. J Vis Exp. 2016 06 14; (112). PMID: 27341402.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    28. Rao W, Pan N, Yang Z. High Resolution Tissue Imaging Using the Single-probe Mass Spectrometry under Ambient Conditions. J Am Soc Mass Spectrom. 2015 Jun; 26(6):986-93. PMID: 25804891.
      Citations: 21     Fields:    
    29. Pan N, Rao W, Kothapalli NR, Liu R, Burgett AW, Yang Z. The single-probe: a miniaturized multifunctional device for single cell mass spectrometry analysis. Anal Chem. 2014 Oct 07; 86(19):9376-80. PMID: 25222919.
      Citations: 50     Fields:    Translation:HumansCells
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